Newcastle Falcons' Mark Wilson wins his 22nd cap for England on Saturday when he starts in the Guinness Six Nations match against France.
The Twickenham clash is a 4.45pm kick-off and is being shown live in the UK on ITV 1, Wilson retaining his place on the blind-side flank.
England head coach Eddie Jones said:“This France game is one we are really looking forward to.
“We are of course disappointed that we can’t defend the championship, but that makes this an even more important game. We want to show what we are capable of.
“The squad have competed really hard in training since Sunday. I believe this is the best 23 to really take the game to France and get us on the front foot.”
15 Max Malins (Bristol Bears, 6 caps)
14 Anthony Watson (Bath Rugby, 49 caps)
13 Henry Slade (Exeter Chiefs, 37 caps)
12 Owen Farrell (Saracens, 91 caps, captain)
11 Jonny May (Gloucester Rugby, 64 caps)
10 George Ford (Leicester Tigers, 75 caps)
9 Ben Youngs (Leicester Tigers, 107 caps)
1 Mako Vunipola (Saracens, 65 caps)
2 Luke Cowan-Dickie (Exeter Chiefs, 29 caps)
3 Kyle Sinckler (Bristol Bears, 42 caps)
4 Maro Itoje (Saracens, 46 caps)
5 Charlie Ewels (Bath Rugby, 19 caps)
6 Mark Wilson (Newcastle Falcons, 21 caps)
7 Tom Curry (Sale Sharks, 31 caps)
8 Billy Vunipola (Saracens, 59 caps)
16 Jamie George (Saracens, 57 caps)
17 Ellis Genge (Leicester Tigers, 26 caps)
18 Will Stuart (Bath Rugby, 10 caps)
19 Jonny Hill (Exeter Chiefs, 7 caps)
20 Ben Earl (Bristol Bears, 11 caps)
21 Dan Robson (Wasps, 10 caps)
22 Ollie Lawrence (Worcester Warriors, 4 caps)
23 Elliot Daly (Saracens, 50 caps)